THEOPENING: A NIH-funded Ph.D. student or postdoctoral fellow position is available on a pulmonary mechanics project in Biomedical Engineering.
THEPROBLEM: In the acute respiratory distress syndrome (ARDS), edema reduces pulmonary gas exchange. Mechanical ventilation assists gas exchange but causes ventilation induced lung injury (VILI) and impedes recovery.
OURAPPROACHANDFINDINGS: In isolated lungs, we made the first surface tension determinations in edematous alveoli. We find that VILI is attributable to heterogeneous lung mechanics, and proportional to surface tension. We have discovered a new property for two existing compounds – the ability to lower surface tension in the lungs.
THEPROJECT: Investigating the mechanism of action of the surface tension-lowering compounds and testing the compounds as treatments for VILI.
QUALIFICATIONS: Applicants should have training in cardiovascular or pulmonary physiology and also, preferably, background in engineering mechanics or biophysics. Ph.D. applicants must hold an undergraduate degree in engineering or in a closely related discipline such as physics. Experience with confocal microscopy or LabView programming is helpful.
THE PI: Carrie E. Perlman trained in mechanical engineering at MIT and biomedical engineering at Northwestern University. She was a postdoctoral fellow in pulmonary physiology at Columbia University.
THEENVIRONMENT: Stevens, in Hoboken, NJ, provides a multidisciplinary research training environment. The beautiful campus is located on the Hudson River, directly opposite and 10 minutes by train from lower Manhattan.
CONTACTINFORMATION: Interested candidates should email Dr. Perlman at email@example.com, and attach a CV.
About Stevens Institute of Technology
Stevens is an equal opportunity employer that is building a diverse faculty, staff and student body and strongly encourages applications from female and minority candidates as well as veterans and individuals with disabilities. Stevens is an NSF ADVANCE institution committed to equitable practices and policies.
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